到目前为止，我发现这种方式有效
from django.core.files.uploadedfile import SimpleUploadedFile
...
def test_form(self):
upload_file = open('path/to/file', 'rb')
post_dict = {'title': 'Test Title'}
file_dict = {'file': SimpleUploadedFile(upload_file.name, upload_file.read())}
form = MyForm(post_dict, file_dict)
self.assertTrue(form.is_valid())
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