Perhabs Tahoma是TrueType字体，您需要首先注册它。根据ReportLab的用户指南，您需要执行以下操作：
from reportlab.pdfbase import pdfmetrics
from reportlab.pdfbase.ttfonts import TTFont
pdfmetrics.registerFont(TTFont('Vera', 'Vera.ttf'))
pdfmetrics.registerFont(TTFont('VeraBd', 'VeraBd.ttf'))
pdfmetrics.registerFont(TTFont('VeraIt', 'VeraIt.ttf'))
pdfmetrics.registerFont(TTFont('VeraBI', 'VeraBI.ttf'))
canvas.setFont('Vera', 32)
canvas.drawString(10, 150, "Some text encoded in UTF-8")
canvas.drawString(10, 100, "In the Vera TT Font!")
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