>>> import re
>>> string = 'YAN300,000,000'
>>> match = re.search(r'([\D]+)([\d,]+)', string)
>>> output = (match.group(1), match.group(2).replace(',',''))
>>> output
('YAN', '300000000')
（感谢zhangyangyu指出我没有完全回答问题）
Python有效地将货币符号和数字拆分为一个字符串
Python有效地将货币符号和数字拆分为一个字符串
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