一些注意事项：
这是我的例子：
import re
import os
import glob
source_dir=os.getcwd()
target_dir="clean"
source_files = [fname for fname in glob.glob(os.path.join(source_dir,"*.seq"))]
# check if target directory exists... if not, create it.
if not os.path.exists(target_dir):
os.makedirs(target_dir)
for source_file in source_files:
target_file = os.path.join(target_dir,os.path.basename(source_file)+".clean")
with open(source_file,'r') as sfile:
with open(target_file,'w') as tfile:
lines = sfile.readlines()
# do the replacement in the second line.
# (remember that arrays are zero indexed)
lines[1]=re.sub("K|Y|W|M|R|S",'N',lines[1])
tfile.writelines(lines)
print "DONE"
希望能帮助到你。
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